SNV-PPILP: refined SNV calling for tumor data using perfect phylogenies and ILP
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چکیده
منابع مشابه
SNV-PPILP: refined SNV calling for tumor data using perfect phylogenies and ILP
MOTIVATION Recent studies sequenced tumor samples from the same progenitor at different development stages and showed that by taking into account the phylogeny of this development, single-nucleotide variant (SNV) calling can be improved. Accurate SNV calls can better reveal early-stage tumors, identify mechanisms of cancer progression or help in drug targeting. RESULTS We present SNV-PPILP, a...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2014
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btu755